Qualifications:

• 2017 Member of the Royal College of Ophthalmologists (MRCOphth)

• 2013 Doctor of Medicine in Research (MD), University of Lausanne, Switzerland

• 2013 Fellowship in Medical Retina and Reading Centre, Moorfields Eye Hospital, London

• 2012 Senior Fellowship in Medical Retina, Manchester Royal Eye Hospital, Manchester

• 2011 Fellowship in Uveitis and Medical Retina, Jules Gonin Eye Hospital, Lausanne

• 2010 Fellow of the European Board of Ophthalmologists (FEBO)

• 2002 Medical Degree, University of Athens, Greece (MB BS)

Director of the Moorfields Ophthalmic Reading Centre (since November 2017): Since taking up the role of Director of the Moorfields Reading centre, I have been working to establish the Reading Centre as a pioneer in the Big Data and Artificial Intelligence ecosystem through academic and commercial collaborations, including with Google DeepMind. Novel, efficient methods of image grading are being developed through the AI pipeline allowing faster turn-around and enabling exploratory projects on novel biomarkers of response to treatment for retinal disease.

Service Delivery Research and Implementation Science: I have a keen interest in new ways of delivering care in Ophthalmology, including with tele-medicine, ‘virtual’ clinics and Artificial Intelligence. I have led two national research projects in the UK funded by the National Institute of Health Research looking at novel care models for Ophthalmology patients, exploring the role of modern imaging and digital technologies. I am developing the role of the Reading Centre as a tele-ophthalmology hub in the context of novel models of care, including ‘virtual clinics’, AI and home-monitoring.

Principal Investigator for Clinical Trials: I have received national recognition as one of the Best Principal Investigators for Clinical Trials in the UK for three consecutive years. This has equipped me with in-depth understanding of the challenges of research governance and clinical trial set-up and monitoring. I am bringing this knowledge and expertise into my current role as Director of the Moorfields Reading Centre.

Delivery of high volume virtual digital clinics in medical retina including diabetic retinopathy, age-related macular degeneration and rapid access pathways- failsafe officer for Moorfields central.

Qualifications:

• 2014-2018: BM BCh Graduate Medicine, Oxford
• 2010-2014: PhD Mouse models for gene therapy, Dundee university
• 2007-2010: BSc(Hons) Molecular medicine, Sussex university

Projects:

• Large dataset analysis in AMD and DMO patients
• Moorfields AI pipeline
• Application of generative adversarial networks in retinal imaging

Expertise:

• Molecular biology
• Gene therapy
• Genetics
• Large data analysis

Dun Jack is an Investigator at Moorfields Eye Hospital. His focus is on using large, multimodal data to develop modern clinical prediction models with techniques such as machine learning. After completing clinical training at the University of Oxford, Dun Jack moved to London for ophthalmology training. He is trained in bioinformatics, molecular biochemistry, high-throughput screening, and bioinformatics through his PhD research as a Wellcome Trust Fellow at the Centre for Dermatology and Genetic Medicine.

Qualifications:

• 2012-2018: MD, Aristotle University of Thessaloniki, Greece
• 2020-2022: MPH, Imperial College London

Professional experience:

• 2018-2019: Junior doctor at Mykonos Health Centre, Greece
• 2020-now: Ophthalmology resident, Hippokration General Hospital, Athens, Greece

Projects:

• Athena study
• EyeNote

Qualifications:

• Degree in Radiotherapy
• Degree in Optometry
• Post-graduation in Advanced Optometry

Qualifications:

• 2022: Fellow of the European Board of Ophthalmologists (FEBO)
• 2019-2021: Doctorate, University of Basel, Switzerland
• 2012-2013: Erasmus Medicine, University of Göttingen, Germany
• 2009-2015: MD, Faculdade de Medicina da Universidade de Lisboa

Professional experience:

• 2023-today: Fellowship in Medical Retina and Reading Centre, Moorfields Eye Hospital, London, UK
• 2022: Ophthalmology Resident, Augenzentrum Bahnhof Basel, Switzerland
• 2021: Internship Pharma-Research and Development, Roche, Switzerland
• 2017-2020: Ophthalmology Resident, Augenklinik Universitätsspital Basel, Switzerland
• 2016-2017: Internal Medicine Resident, Felix-Platter Spital, Basel, Switzerland

Projects:

• Automated Machine Learning in Ophthalmology on macular OCT and retinal fundus photographs
• Data linkage: Retinal Imaging and Systemic disease

Dr Cathy Egan is a world-renowned retinal expert and lead for the MacTel trial at the Moorfields Reading Centre.

Dr Egan has published extensively on novel imaging and automated grading for Diabetic Retinopathy. Her pioneering work on the MacTel study has engendered new insight into this condition and has demonstrated the crucial role of ophthalmic imaging for refined phenotyping of retinal disease.

Dr Egan is lead for the diabetic retinopathy service at Moorfields Eye Hospital.

Qualification:

• PhD and MSc Human Nutrition, Granada University Spain

• BSc Biology, West University Romania

Responsibilities:

• Grading for Bio Bank studies

• Screening/grading for diabetic retinopathy –face to face contact with patients

• Data management for clinical trials

• Statistical analysis

• Conduct clinical trial, responsible from open and lock trial, patient recruitment, monitoring, cross-checking.

I am interested in seeing how nutrition impacts on health and disease and how it can improve day-to-day life. I have expertise in grading for UKBioBank studies, screening/grading for diabetic retinopathy –face to face contact with patients and Data management for clinical trials

Qualifications:

• 2023: Medical Retina Professional Certificate, City University

• 2016: Optometry BSc (Hons), Cardiff University

• Glaucoma and Cataract LOCSU

• Peter Yeo Memorial Award for Optometric Practice

• Liles Research Project Award

Experience:

• Grader for studies with data sets including RATE, OAKS and DERBY.

• Clinical collaboration on research studies including ATHENA, HERMES and new referral refinement pathways.

• Clinical tutor at City University.

• Specialist contact-lens technician on film sets.

• Specialist Optometrist in Independent practice running a myopia control clinic.

Qualifications:

• MSc Biomedical Sciences, Kingston University UK

• BSc Biomedical Sciences, King’s College London, UK

Expertise:

Grading for Diabetic retinopathy screening, NetwoRC UK studies, epidemiological studies, PEEK smartphone grading and working on the Cleopatra clinical trial.

Dr Heeren is an Ophthalmologist with specialist interest in Medical Retina. He has a particular research interest in Macular Telangiectasia type II and has pioneered image analysis methods that offered new insight into the understanding of this rare disease. Dr Heeren is involved in a number of imaging, clinical and basic science research projects pertaining to MacTel.

Dr. Philipp L. Müller received his medical and doctoral degree from the Julius-Maximilians University School of Medicine, Würzburg, Germany. He trained in Ophthalmogy at University of Bonn, Germany. Where he continued to work as Consultant and Post-Doctoral Clinician Scientist. Since 2019, Dr. Müller works as Honorary Research Fellow at Moorfields Eye Hospital, London, UK.

His special interest is research for retinal diseases and novel retinal imaging technologies as well as data science and machine leaning applications in healthcare. He has evaluated and established multiple novel imaging and image analysis methods that offered new insight into the understanding of retinal disease entities which has been awarded multiple times.

Dr. Müller is involved in numerous projects dealing with imaging, image analysis, big data science and the application of artificial intelligence in Ophthalmology.

Dr Khalid is leading a number of research projects involving the role of OCT angiography in the diagnosis and management of chorio-retinal disease, including in wide-field OCT angiography

Qualifications: * BA (Hons)

Irene has contributed to over 50 publications on Mactel, DR and AMD. She has supported multiple AI projects over the years as well as contributed to Diabetic retinopathy screening, NetwoRC UK studies, epidemiological studies, PEEK smartphone grading and the Cleopatra clinical trial.

Qualifications: * BSc (Hons) Optometry - Anglia Ruskin University - 2006 * Certificate in Diabetic Retinopathy Screening - City and Guilds - 2012 * LOCSU Low Vision Theory - WOPEC - 2014 * Professional Certificate in Glaucoma - City University of London - 2019 * NOCN Level 3 Certificate in Assessing Vocational Achievement - NOCN - 2023 * Higher Certificate in Glaucoma - UCL - in progress 2022-23 * MECS - WOPEC - in progress 2022-23

Experience: * Grader for the RATE study. * Involved in recruitment for the ATHENA study, checking for patient eligibility from referral letters and associated OCT scans and imaging. This also involves links to the COAST recruitment team and flagging possible eligible patients to them. * Involved in triaging for referral refinement schemes such as SPoA and St George’s in South West London, using OPERA system from community Optometrists using the CUES-MECS pathways, eRS portals and NHS.net email links. * Failsafe for Medical retina virtual clinics (including the rapid access clinics for urgent suspect wet AMD/maculopathy cases) across City Road and Hoxton sites. * Previous experience in reviewing the Medical Retina virtual clinics including diagnosing MR conditions from OCT scans and imaging as well as patient history, arranging appropriate treatment and follow up appointments and communicating with the patients, GPs and relevant clinical teams. * Previous experience working in the Medical Retina intravitreal injection clinics, treating patients with various conditions including AMD, retinal vein occlusions, diabetic eye disease, hereditary eye conditions. * Ongoing work in Optom-Led glaucoma clinics at City Road as well as the Optometry Refraction and Low Vision clinics. * Over 10 years’ experience grading at a primary and secondary level in diabetic eye screening programmes as well as conducting slit lamp clinics for those patients who cannot undertake the usual imaging or whose images are ungradable. This also involves training up new staff with slit lamp skills and OCT interpretation.

Alexandra has expertise in delivery of high volume virtual digital clinics in medical retina including diabetic retinopathy, age-related macular degeneration and rapid access pathways.